ADJUST, Again

VTE is VTE, whether PE or DVT!

You can age-adjust your D-dimer for pulmonary embolism.

Logically – and now, proven so – you can also age-adjust your D-dimer for lower extremity deep venous thrombosis. See:

Adding the diagonal line of age-adjusted cut-off to the typical D-dimer cutoff carves out an additional cohort of true negatives, and the failure rate of the algorithm remains unchanged.

Now – how can we combine 4D with ADJUST-DVT and safely exclude even more?