About a decade ago, the results of the TACT trial were published, demonstrating the apparent benefit of chelation therapy for prevention of adverse cardiovascular outcomes. These findings were viewed – can we say – skeptically by the medical community, as chelation therapy long held a reputation as pseudoscientific garbage.
In view of these unexpected positive results, TACT2 was planned to confirm these initial observations – and enrolled approximately 1,000 patients in a 2x2 factorial design testing high doses of oral multivitamins and multiminerals against placebo, and EDTA chelation therapy against placebo.
The TACT2 EDTA chelation outcomes – no effect – have been published previously. Now, the multivitamin report. The key figure from this article is here:
So, there you go – no advantage from EDTA, no advantage from high-dose multivitamins. Yet another example where well-conducted scientific evidence fails to support magical protective power from vitamins – a $50 billion waste in the U.S. alone.